The standard for fame as far as cameos in cartoons go is probably still The Simpsons, but American Dad ain't nothing to sneeze at.
In an episode set to air Nov. 22, American Dad's title character becomes obsessed with the group and decides to become a My Morning Jacket groupie, probably the only one without a beard and a one-hitter. Look at more images from the upcoming episode here.
My Morning Jacket »
ewww.