My vote is for 'Scarface.'

http://www.imdb.com/title/tt0086250/quotes

Tony Montana: What you lookin' at? You all a bunch of fuckin' assholes. You know why? You don't have the guts to be what you wanna be? You need people like me. You need people like me so you can point your fuckin' fingers and say, "That's the bad guy." So... what that make you? Good? You're not good. You just know how to hide, how to lie. Me, I don't have that problem. Me, I always tell the truth. Even when I lie. So say good night to the bad guy! Come on. The last time you gonna see a bad guy like this again, let me tell you. Come on. Make way for the bad guy. There's a bad guy comin' through! Better get outta his way! 

I'd nominate Pee-Wee's Big Adventure:

"I mean, everyone wanted my bike. Just this morning Francis offered to...FRANCIS!"

"Francis is Busy, he's having his bath! Oh really? Where are they hosing him down?"

"What's your name boy?

I don't remember.

Where you from boy?

I don't remember.

Well, what do you remember?

I remember, the Alamo"

"I'm a loner Dotty. A rebel. You don't want to get mixed up with a guy like me."

happy gilmore:

shooter: I eat peices of shit like you for breakfast.

happy: You eat peices of shit for breakfast?

shooter: NO!

shooter: Just stay out of my way, or you'll pay... LISTEN to what I say.

happy: How bout I just go eat some hay? I can make things out of clay and lay by the bay, what do ya say!?

Grandma: Sir, can I trouble you for a glass of warm milk? It helps me go to sleep.
Nursing Home Orderly: You can trouble me for a warm glass of shut-the-hell-up! Now, you will go to sleep! Or I will PUT you to sleep. Check out the name tag. You're in MY world now, grandma!

Old school. with "'sir your seatbelt appears to be broken, what do you recommend I do?' 'I recommend you stop being such a faggot, you're in the backseat'"...

Major League? Pulp Fiction? For me It's 10 Things I Hate About You...

Bianca: There's a difference between like and love. Because, I like my Skechers, but I love my Prada backpack.
Chastity: But I love my Skechers.
Bianca: That's because you don't have a Prada backpack.

Bianca: Where did you come from? Planet "Loser"?
Kat Stratford: As opposed to Planet "Look At Me, Look At Me"?

Jurassic Park.

Tons of gold.

This Is Spinal Tap. "It goes to 11."

Napoleon Dynamite. Hey, Napoleon, what did you do last summer. "I told you! I spent it with my uncle in Alaska hunting wolverines."

Caddyshack. "A cinderella story..."

On the Waterfront. "I coulda been a contender."

Apocalypse Now. "I love the smell of napalm in the morning..."

Taxi Driver. "You talkin' to me?'

Godfather. "I'd made him an offer he couldn't refuse."

But the winner has to be ...drum roll... TOP GUN. Fav line: Tower, this is Ghost Rider requesting a flyby. "NEGATIVE GHOST RIDER! the pattern is full."

lol @ kwaping. Don't tell me Daba has you drinking the DipSeth haterade too. 10 things da best!

brandons post was awesome.

dipseths... not so much

OK, to make up for my lack of testosterone, I present the quote machine that is Wet Hot American Summer:

Caped Boy: Excuse me, ladies. You may remember me as the guy who came to dinner a few weeks ago with underwear on my head. My name is Keith Stat from Millburn, New Jersey. State bird, the mosquito. And as you may have heard, I am recently a crowned class B dungeon master. So if any of you would like to play D&D today, please speak now or forever hold your peace.
[he chuckles, and there is an awkward silence at the table]
Caped Boy: Anyone? Alexa!
[Alexa gives him a withering glare]
Caped Boy: Maybe you would like to join in? We do need a druid, and you have definitely cast a level 5 charm spell on me.
Alexa: In your dreams, douche-bag!
Caped Boy: Douche-bags are hygienic products; I take that as a compliment. Thank you.
[Keith walks off]
Alexa: Ewww!